Quantum annealing combined with a Neural Hash Function lets generative models create molecules that are more drug-like than classical versions or the training set itself.
Distribution Matching in Variational Inference
1 Pith paper cite this work. Polarity classification is still indexing.
1
Pith paper citing it
abstract
With the increasingly widespread deployment of generative models, there is a mounting need for a deeper understanding of their behaviors and limitations. In this paper, we expose the limitations of Variational Autoencoders (VAEs), which consistently fail to learn marginal distributions in both latent and visible spaces. We show this to be a consequence of learning by matching conditional distributions, and the limitations of explicit model and posterior distributions. It is popular to consider Generative Adversarial Networks (GANs) as a means of overcoming these limitations, leading to hybrids of VAEs and GANs. We perform a large-scale evaluation of several VAE-GAN hybrids and analyze the implications of class probability estimation for learning distributions. While promising, we conclude that at present, VAE-GAN hybrids have limited applicability: they are harder to scale, evaluate, and use for inference compared to VAEs; and they do not improve over the generation quality of GANs.
fields
q-bio.QM 1years
2026 1verdicts
UNVERDICTED 1representative citing papers
citing papers explorer
-
Molecular Design beyond Training Data with Novel Extended Objective Functionals of Generative AI Models Driven by Quantum Annealing Computer
Quantum annealing combined with a Neural Hash Function lets generative models create molecules that are more drug-like than classical versions or the training set itself.