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Mitigating the missing-fragmentation problem in de novo peptide sequencing with a two-stage graph-based deep learning model

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cs.LG 1

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2025 1

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CONDITIONAL 1

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Diffusion Decoding for Peptide De Novo Sequencing

cs.LG · 2025-07-15 · conditional · novelty 4.0

A diffusion decoder with DINOISER loss raises amino acid recall from 0.081 to 0.454 in Casanovo, while peptide precision and coverage stay at 0 and predicted sequences are much longer than the true peptides.

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  • Diffusion Decoding for Peptide De Novo Sequencing cs.LG · 2025-07-15 · conditional · none · ref 7

    A diffusion decoder with DINOISER loss raises amino acid recall from 0.081 to 0.454 in Casanovo, while peptide precision and coverage stay at 0 and predicted sequences are much longer than the true peptides.