Geometric stability, defined as the directional coherence of cellular responses to perturbation, provides a framework for assessing whether resulting cellular states are stable beyond conventional metrics of intervention success.
Chromatin accessibility and guide sequence secondary structure affect CRISPR-Cas9 gene editing efficiency
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From Syntax to Semantics: Geometric Stability as the Missing Axis of Perturbation Biology
Geometric stability, defined as the directional coherence of cellular responses to perturbation, provides a framework for assessing whether resulting cellular states are stable beyond conventional metrics of intervention success.