Phase separation of protein-RNA condensates is encoded by specific chemical interactions between individual dipeptides and nucleobases, with bases acting as tuners that dissolve, stabilize, or fluidize the assemblies.
Computational ap- proaches to predict protein–protein interactions in crowded cellular environments.Chemical Reviews, 124(7):3932–3977
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Deciphering the chemical grammar of protein-RNA condensates
Phase separation of protein-RNA condensates is encoded by specific chemical interactions between individual dipeptides and nucleobases, with bases acting as tuners that dissolve, stabilize, or fluidize the assemblies.