Activation steering can guide protein language models to generate and optimize sequences with higher predicted thermostability, solubility, or GFP brightness, but only in surrogate-based evaluation.
Bioinformatics approaches for improved recombinant protein production in escherichia coli: protein solubility prediction.Briefings in bioinformatics, 15(6):953–962, 2014
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Steering Protein Language Models
Activation steering can guide protein language models to generate and optimize sequences with higher predicted thermostability, solubility, or GFP brightness, but only in surrogate-based evaluation.