In a stochastic ribosome-traffic model with antibiotic-induced pauses and finite mRNA lifetimes, longer transcripts suffer disproportionately stronger translation inhibition, driven by collective ribosome dynamics rather than single-ribosome kinetics.
Title resolution pending
1 Pith paper cite this work, alongside 152 external citations. Polarity classification is still indexing.
1
Pith paper citing it
152
external citations · OpenAlex
citation-role summary
background 1
citation-polarity summary
fields
q-bio.SC 1years
2025 1verdicts
CONDITIONAL 1roles
background 1polarities
unclear 1representative citing papers
citing papers explorer
-
Paused in translation: A model for the transcript length-dependent impact of ribosome-targeting antibiotics
In a stochastic ribosome-traffic model with antibiotic-induced pauses and finite mRNA lifetimes, longer transcripts suffer disproportionately stronger translation inhibition, driven by collective ribosome dynamics rather than single-ribosome kinetics.