VibeProteinBench is a new benchmark evaluating LLMs on open-ended language-interfaced protein design across recognition, engineering, and generation, with no model showing strong performance in all areas.
Machine learning for functional protein design.Nature biotechnology, 42(2):216–228
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EvoIF integrates within-family and cross-family evolutionary signals into a compact model to achieve competitive or state-of-the-art zero-shot fitness prediction on ProteinGym using only 0.15% of typical training data.
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VibeProteinBench: An Evaluation Benchmark for Language-interfaced Vibe Protein Design
VibeProteinBench is a new benchmark evaluating LLMs on open-ended language-interfaced protein design across recognition, engineering, and generation, with no model showing strong performance in all areas.
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Evolutionary Profiles for Protein Fitness Prediction
EvoIF integrates within-family and cross-family evolutionary signals into a compact model to achieve competitive or state-of-the-art zero-shot fitness prediction on ProteinGym using only 0.15% of typical training data.