In the SIMS model, star-like mutational clusters cause oscillatory seasonal outbreaks while lattice-like networks give stable endemic states, and simulated strain emergence order correlates with H3N2 sampling times.
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Genotype networks drive oscillating endemicity and epidemic trajectories in viral evolution
In the SIMS model, star-like mutational clusters cause oscillatory seasonal outbreaks while lattice-like networks give stable endemic states, and simulated strain emergence order correlates with H3N2 sampling times.