T cells with intermediate stimulation uptake benefit most from dendritic cell clustering, showing comparable or greater activation abundance and higher heterogeneity than with low clustering.
The serial engagement model 17 years after: from TCR triggering to im- munotherapy
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Spatial dynamic modelling to understand how dendritic cell clustering affects T cell activation
T cells with intermediate stimulation uptake benefit most from dendritic cell clustering, showing comparable or greater activation abundance and higher heterogeneity than with low clustering.