A categorical preorder on trial tallies reveals a new monotonicity flaw in the 3+3 dose-escalation design and yields right Kan and Galois extensions that support titration.
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Dose-Escalation Trial Protocols that Extend Naturally to Admit Titration
A categorical preorder on trial tallies reveals a new monotonicity flaw in the 3+3 dose-escalation design and yields right Kan and Galois extensions that support titration.