Phase separation of protein-RNA condensates is encoded by specific chemical interactions between individual dipeptides and nucleobases, with bases acting as tuners that dissolve, stabilize, or fluidize the assemblies.
Sequestration within biomolecular con- densates inhibits aβ-42 amyloid formation.Chem- ical Science, 12(12):4373–4382
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Deciphering the chemical grammar of protein-RNA condensates
Phase separation of protein-RNA condensates is encoded by specific chemical interactions between individual dipeptides and nucleobases, with bases acting as tuners that dissolve, stabilize, or fluidize the assemblies.