Genetic deletion of Pyk2 prevents amyloid-beta oligomer-induced hippocampal neuronal hyperactivity and synaptic loss while decreasing Tau synaptic localization in the mouse hippocampus.
RAFTK/Pyk2 Activation Is Mediated by Trans -acting Autophosphorylation in a Src -independent Manner
1 Pith paper cite this work. Polarity classification is still indexing.
1
Pith paper citing it
fields
q-bio.NC 1years
2025 1verdicts
CONDITIONAL 1representative citing papers
citing papers explorer
-
Pyk2 plays a critical role in synaptic dysfunction during the early stages of Alzheimer's disease
Genetic deletion of Pyk2 prevents amyloid-beta oligomer-induced hippocampal neuronal hyperactivity and synaptic loss while decreasing Tau synaptic localization in the mouse hippocampus.