A domain-adaptive fine-tuning stage followed by reward-weighted RL fine-tuning produces protein sequences whose amino-acid composition matches a specified target while preserving sequence statistics and diversity.
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Two-Stage Fine-Tuning for Protein Sequence Generation with Targeted Amino-Acid Composition
A domain-adaptive fine-tuning stage followed by reward-weighted RL fine-tuning produces protein sequences whose amino-acid composition matches a specified target while preserving sequence statistics and diversity.