A new tree-conditioned edit-flow model for ancestral sequence reconstruction achieves reasonable accuracy on substitution-only evolved sequences and superior localization of changes on natural indel-rich sequences.
Maximum likelihood and minimum-steps methods for estimating evolutionary trees from data on discrete characters.Systematic Biology, 22(3):240–249, 09 1973
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Tree-Conditioned Edit Flows for Ancestral Sequence Reconstruction
A new tree-conditioned edit-flow model for ancestral sequence reconstruction achieves reasonable accuracy on substitution-only evolved sequences and superior localization of changes on natural indel-rich sequences.