A conductance-based network model shows that the fraction of inhibitory synaptic conductance driving chloride influx organizes seizures into distinct pre-ictal, tonic, and clonic stages with characteristic dynamics.
Neuronal chloride and excitability—the big im- pact of small changes.Current opinion in neurobiology, 43:35–42
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Role of chloride concentration in modulating seizure transitions in excitatory and inhibitory networks
A conductance-based network model shows that the fraction of inhibitory synaptic conductance driving chloride influx organizes seizures into distinct pre-ictal, tonic, and clonic stages with characteristic dynamics.