Phase separation of protein-RNA condensates is encoded by specific chemical interactions between individual dipeptides and nucleobases, with bases acting as tuners that dissolve, stabilize, or fluidize the assemblies.
Liquid-liquid phase separation and fibrillation of the prion protein modulated by a high-affinity dna aptamer.The FASEB Journal, 34(1):365–385
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Deciphering the chemical grammar of protein-RNA condensates
Phase separation of protein-RNA condensates is encoded by specific chemical interactions between individual dipeptides and nucleobases, with bases acting as tuners that dissolve, stabilize, or fluidize the assemblies.