Semiaddressable binding, where each species binds itself and the next in sequence, yields a tunable filament length distribution whose mean and width are independently controlled.
Length Regulation Drives Self-Organization in Filament-Motor Mixtures
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Cytoskeletal networks form complex intracellular structures. Here we investigate a minimal model for filament-motor mixtures in which motors act as depolymerases and thereby regulate filament length. Combining agent-based simulations and hydrodynamic equations, we show that resource-limited length regulation drives the formation of filament clusters despite the absence of mechanical interactions between filaments. Even though the orientation of individual remains fixed, collective filament orientation emerges in the clusters, aligned orthogonal to their interfaces.
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Stochastic size control of self-assembled filaments
Semiaddressable binding, where each species binds itself and the next in sequence, yields a tunable filament length distribution whose mean and width are independently controlled.