A mathematical model of enhancer-based gene regulation shows that hierarchical cell identities and progenitor states emerge from competition between enhancers for epigenetic readers, predicting observed blood progenitor states.
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Hierarchical cell identities emerge from animal gene regulatory mechanisms
A mathematical model of enhancer-based gene regulation shows that hierarchical cell identities and progenitor states emerge from competition between enhancers for epigenetic readers, predicting observed blood progenitor states.