Germline-absorbing discrete diffusion uses the germline sequence as the absorbing state to reduce germline bias in antibody modeling, raising non-germline residue prediction accuracy from 26% to 46% and improving conditional generation tradeoffs over EvoProtGrad.
Clustering huge protein sequence sets in linear time
2 Pith papers cite this work. Polarity classification is still indexing.
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2026 2verdicts
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MIMIC is a split-track encoder-decoder foundation model that unifies sequence reconstruction, prediction, and constrained design across nucleic acids, proteins, and regulatory context using partially observed multimodal inputs.
citing papers explorer
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Conditional generation of antibody sequences with classifier-guided germline-absorbing discrete diffusion
Germline-absorbing discrete diffusion uses the germline sequence as the absorbing state to reduce germline bias in antibody modeling, raising non-germline residue prediction accuracy from 26% to 46% and improving conditional generation tradeoffs over EvoProtGrad.
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MIMIC: A Generative Multimodal Foundation Model for Biomolecules
MIMIC is a split-track encoder-decoder foundation model that unifies sequence reconstruction, prediction, and constrained design across nucleic acids, proteins, and regulatory context using partially observed multimodal inputs.