A benchmark of three PPI predictors shows they miss many known viral-host interactions and all four tested ACE2-binding spike mutants, underpinning a call for response-oriented biosecurity.
Ruffolo and Ali Madani
1 Pith paper cite this work, alongside 97 external citations. Polarity classification is still indexing.
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Resilient Biosecurity in the Era of AI-Enabled Bioweapons
A benchmark of three PPI predictors shows they miss many known viral-host interactions and all four tested ACE2-binding spike mutants, underpinning a call for response-oriented biosecurity.