AbICL adapts antibody affinity ranking at test time by conditioning on labeled pairwise comparisons through a transformer context head trained with episodic meta-learning, achieving improved AUROC on the AbRank benchmark.
Sequence-only pre- diction of binding affinity changes: a robust and inter- pretable model for antibody engineering.Bioinformatics, 41(8):btaf446, 2025
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AbICL: In-Context Learning for Antigen-Specific Antibody Affinity Ranking
AbICL adapts antibody affinity ranking at test time by conditioning on labeled pairwise comparisons through a transformer context head trained with episodic meta-learning, achieving improved AUROC on the AbRank benchmark.