An end-to-end simulation framework chains transcranial ultrasound pressure, tissue strain, brain temperature, and a multi-pathway Hodgkin-Huxley neuron to produce anatomy-registered per-voxel firing maps, demonstrated on a human skull model.
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An open-source framework for predicting ultrasound neuromodulation: bridging tissue elastomechanics and neuron firing dynamics
An end-to-end simulation framework chains transcranial ultrasound pressure, tissue strain, brain temperature, and a multi-pathway Hodgkin-Huxley neuron to produce anatomy-registered per-voxel firing maps, demonstrated on a human skull model.