A Bayesian joint model of two-compartment tumor growth and multistate survival hazards forecasts PFS/OS from early oncology data, demonstrated in SCLC with forecasts 8 months before maturity.
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PIONEER: Bayesian Joint Modelling of Mechanistic Tumour Growth and Time-to-Event Endpoints for Dynamic Prediction of Ongoing Oncology Trials
A Bayesian joint model of two-compartment tumor growth and multistate survival hazards forecasts PFS/OS from early oncology data, demonstrated in SCLC with forecasts 8 months before maturity.