An agent-based extension of the GSM2 model simulates cell-cycle dynamics and reproduces dose-rate and fractionation effects in particle-irradiated tumor spheroids through explicit stochastic damage and repair processes.
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2026 1verdicts
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A stochastic agent-based extension of the GSM2 model for particle therapy: cell-cycle dynamics, dose-rate dependence, and fractionation effects
An agent-based extension of the GSM2 model simulates cell-cycle dynamics and reproduces dose-rate and fractionation effects in particle-irradiated tumor spheroids through explicit stochastic damage and repair processes.