Neutralization titers follow Gumbel distributions indicating influenza polyclonal responses are either collective or dominated by few strong binders, captured quantitatively by an equilibrium binding model.
(2026) High-throughput neutralization measurements correlate strongly with evolutionary suc- cess of human influenza strains.eLife14:RP106811
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Neutralization titers reveal the structure of polyclonal antibody responses
Neutralization titers follow Gumbel distributions indicating influenza polyclonal responses are either collective or dominated by few strong binders, captured quantitatively by an equilibrium binding model.