MR-CCC is a Bayesian MR framework that uses cis-eQTL instruments and receptor-modulated interaction terms to identify causal cell-cell communication, recovering eight signaling pathways in NK-to-monocyte data.
Identification of CD72 as a lymphocyte receptor for the class IV semaphorin CD100: a novel mechanism for reg- ulating B cell signaling.Immunity, 13(5):621–631
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MR-CCC: Bayesian Mendelian Randomization for Causal Cell--Cell Communication
MR-CCC is a Bayesian MR framework that uses cis-eQTL instruments and receptor-modulated interaction terms to identify causal cell-cell communication, recovering eight signaling pathways in NK-to-monocyte data.