A two-compartment spiking model shows that boosting coupling or apical drive raises pyramidal gain, and that the associated bursting accelerates STDP updates, yielding fast and slow weight changes.
R.et al.Neuronal connected burst cascades bridge macroscale adaptive signatures across arousal states.Nat
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The role of gain neuromodulation in layer-5 pyramidal neurons
A two-compartment spiking model shows that boosting coupling or apical drive raises pyramidal gain, and that the associated bursting accelerates STDP updates, yielding fast and slow weight changes.