A closed-loop workflow using Gaussian process surrogate modeling and Bayesian optimization, updated over ten iterations with 106 wet-lab tests, adapted from literature data to identify a cryoprotectant formulation achieving 95.15% post-thaw viability for cryomicroneedles.
Mi- croneedles in the clinic.Journal of Controlled Release, 260:164–182, August 2017
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Agentic Discovery of Cryomicroneedle Formulations
A closed-loop workflow using Gaussian process surrogate modeling and Bayesian optimization, updated over ten iterations with 106 wet-lab tests, adapted from literature data to identify a cryoprotectant formulation achieving 95.15% post-thaw viability for cryomicroneedles.