PTMs have type-dependent effects on protein backbone flexibility: N-glycosylation has little effect, CDK2 phosphorylation rigidifies the site and destabilizes two distant phosphorylation regions, and actin methylation increases local deformation.
induced folding
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Investigation of the impact of PTMs on the protein backbone conformation
PTMs have type-dependent effects on protein backbone flexibility: N-glycosylation has little effect, CDK2 phosphorylation rigidifies the site and destabilizes two distant phosphorylation regions, and actin methylation increases local deformation.