A minimal model of coupled metabolic currencies reveals a tradeoff where independent regulation requires comparable metabolite abundances at the cost of higher entropy production.
Sueoka, Correlation between base composition of de- oxyribonucleic acid and amino acid composition of pro- tein, Proceedings of the National Academy of Sciences 47, 1141 (1961)
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Thermodynamic cost-controllability tradeoff in metabolic currency coupling
A minimal model of coupled metabolic currencies reveals a tradeoff where independent regulation requires comparable metabolite abundances at the cost of higher entropy production.