A three-scale mechanical model predicts that axon growth cones generate stiffness-dependent traction with an optimal stiffness, producing positive or negative durotaxis, attraction to optimal-stiffness lines, and reflection or refraction at stiffness boundaries.
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The multiscale mechanics of axon durotaxis
A three-scale mechanical model predicts that axon growth cones generate stiffness-dependent traction with an optimal stiffness, producing positive or negative durotaxis, attraction to optimal-stiffness lines, and reflection or refraction at stiffness boundaries.