Interplay-robust optimization, which models the timing between beam delivery and breathing motion during planning, improves target coverage and reduces organ-at-risk doses compared with conventional 4D robust optimization in simulated irregular-breathing lung patients.
A review of the clinical introduction of 4D particle therapy research concepts
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Interplay-robust optimization for treating irregularly breathing lung patients with pencil beam scanning
Interplay-robust optimization, which models the timing between beam delivery and breathing motion during planning, improves target coverage and reduces organ-at-risk doses compared with conventional 4D robust optimization in simulated irregular-breathing lung patients.