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doi:10 · DOI 10.1002/cpt.2575

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Estimands for Randomized Discontinuation Designs in Oncology

stat.ME · 2025-05-31 · conditional · novelty 5.0

Maps the ICH E9(R1) estimand framework onto oncology randomized discontinuation trials, showing population and treatment attributes differ from traditional RCTs while intercurrent-event handling is similar when anchored at randomization.

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  • Estimands for Randomized Discontinuation Designs in Oncology stat.ME · 2025-05-31 · conditional · none · ref 19

    Maps the ICH E9(R1) estimand framework onto oncology randomized discontinuation trials, showing population and treatment attributes differ from traditional RCTs while intercurrent-event handling is similar when anchored at randomization.