MERGE-RNA uses maximum-entropy modeling of the DMS probing pipeline to learn a small set of transferable parameters that predict RNA secondary structure ensembles matching experimental reactivity better than standard pseudo-free-energy approaches.
Fast algorithm for predicting the secondary structure of single-stranded RNA.Proceedings of the National Academy of Sciences, 77(11):6309–6313, November 1980
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MERGE-RNA: a physics-based model to predict RNA secondary structure ensembles with chemical probing
MERGE-RNA uses maximum-entropy modeling of the DMS probing pipeline to learn a small set of transferable parameters that predict RNA secondary structure ensembles matching experimental reactivity better than standard pseudo-free-energy approaches.