Bayesian group-sequential trials are not immune to multiplicity: interim analyses inflate Type I error and degrade Bayesian discovery odds, with sensitivity to prior mismatch growing in the number of looks.
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Impact of interim analyses on Bayesian and frequentist operating characteristics of Bayesian clinical trials
Bayesian group-sequential trials are not immune to multiplicity: interim analyses inflate Type I error and degrade Bayesian discovery odds, with sensitivity to prior mismatch growing in the number of looks.