AbICL adapts antibody affinity ranking at test time by conditioning on labeled pairwise comparisons through a transformer context head trained with episodic meta-learning, achieving improved AUROC on the AbRank benchmark.
Predicting antibody–antigen affinity with a dual-level representation model.Bioinformatics, 42(4):btag109, 04 2026
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AbICL: In-Context Learning for Antigen-Specific Antibody Affinity Ranking
AbICL adapts antibody affinity ranking at test time by conditioning on labeled pairwise comparisons through a transformer context head trained with episodic meta-learning, achieving improved AUROC on the AbRank benchmark.