Across six SARS-CoV-2 variants, tighter ACE2 binding is associated with greater rigidity of the unbound spike RBD and with dynamics that resemble the bound state.
Computational approaches to predict protein–protein interactions in crowded cellular environments
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Insights into the role of dynamical features in protein complex formation: the case of SARS-CoV-2 spike binding with ACE2
Across six SARS-CoV-2 variants, tighter ACE2 binding is associated with greater rigidity of the unbound spike RBD and with dynamics that resemble the bound state.