PyBioNetFit is demonstrated to formalize qualitative observations from a 2013 signaling study and combine them with quantitative data to parameterize an ODE model while enabling uncertainty quantification that was absent in prior manual tuning.
Then, following the inference approach of Mitra et al
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Using PyBioNetFit to Leverage Qualitative and Quantitative Data in Biological Model Parameterization and Uncertainty Quantification
PyBioNetFit is demonstrated to formalize qualitative observations from a 2013 signaling study and combine them with quantitative data to parameterize an ODE model while enabling uncertainty quantification that was absent in prior manual tuning.