CellRefine adds a marker-gene-guided post-pretraining stage to single-cell models that refines the cell embedding manifold and improves downstream task performance by up to 15%.
edger: a bioconductor package for differential expression analysis of digital gene expression data.Bioinformatics, 26(1):139–140
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Prototype Guided Post-pretraining for Single-Cell Representation Learning
CellRefine adds a marker-gene-guided post-pretraining stage to single-cell models that refines the cell embedding manifold and improves downstream task performance by up to 15%.