ProfileBFN adapts Bayesian flow networks to accept protein-family profiles, enabling diverse, novel, and apparently functional family protein generation from single-sequence training.
In the light of directed evolution: pathways of adaptive protein evolution
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Steering Protein Family Design through Profile Bayesian Flow
ProfileBFN adapts Bayesian flow networks to accept protein-family profiles, enabling diverse, novel, and apparently functional family protein generation from single-sequence training.