A text-guided 3D diffusion model generates synthetic tau PET images from MRI anatomy and plasma p-tau217 levels, reproducing Alzheimer's tau progression patterns.
Regional profiles of the candidate tau pet ligand 18 f-av-1451 recapitulate key features of braak histopathological stages,
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TauGenNet: Plasma-Driven Tau PET Image Synthesis via Text-Guided 3D Diffusion Models
A text-guided 3D diffusion model generates synthetic tau PET images from MRI anatomy and plasma p-tau217 levels, reproducing Alzheimer's tau progression patterns.