A new benchmarking framework shows virtual cell models overestimate performance on standard tests, drop sharply on unseen contexts and perturbations, and produce inconsistent rankings across metrics.
Massively multiplex chemical transcriptomics at single-cell resolution.Science, 367(6473): 45–51
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Benchmarking virtual cell models for in-the-wild perturbation response
A new benchmarking framework shows virtual cell models overestimate performance on standard tests, drop sharply on unseen contexts and perturbations, and produce inconsistent rankings across metrics.