An integrated model of inflammation, temperature, pain, and cardiovascular dynamics is fitted to two human endotoxin studies, and its simulations predict that multimodal therapy beats single drugs.
Severe sepsis and septic shock: review of the literature and emergency department management guidelines
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A physiological model of the inflammatory-thermal-pain-cardiovascular interactions during a pathogen challenge
An integrated model of inflammation, temperature, pain, and cardiovascular dynamics is fitted to two human endotoxin studies, and its simulations predict that multimodal therapy beats single drugs.