GCE-MIL is a backbone-agnostic wrapper that directly optimizes MIL evidence for sufficiency, necessity, and recoverability, yielding modest gains in Macro-F1 and C-index plus more faithful patch selection across many backbones and datasets.
Nature biomedical engineering , volume=
6 Pith papers cite this work. Polarity classification is still indexing.
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Standard MIL models for whole-slide pathology images exhibit spatial blindness under coordinate permutation; ResTopoMIL separates appearance and spatial learning to restore sensitivity and improve classification and survival prediction.
HEXST applies a hexagonal shifted-window Transformer with rotary positional encodings, contrast-sensitive training objectives, and single-cell priors to predict gene expression from histology slides, outperforming prior models on seven datasets while preserving spatial heterogeneity.
Multi-Beholder integrates one-class classification into multiple instance learning to predict LGG biomarker status from histopathology images, reporting AUCs of 0.973 on TCGA-LGG and 0.820 on an external Xiangya cohort.
FedHD is a federated learning framework for whole slide images that distills one-to-one synthetic features aligned via Gaussian mixtures and progressively integrates cross-site features through curriculum learning to handle institutional heterogeneity.
citing papers explorer
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GCE-MIL: Faithful and Recoverable Evidence for Multiple Instance Learning in Whole-Slide Imaging
GCE-MIL is a backbone-agnostic wrapper that directly optimizes MIL evidence for sufficiency, necessity, and recoverability, yielding modest gains in Macro-F1 and C-index plus more faithful patch selection across many backbones and datasets.
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Spatial Blindness in Whole-Slide Multiple Instance Learning
Standard MIL models for whole-slide pathology images exhibit spatial blindness under coordinate permutation; ResTopoMIL separates appearance and spatial learning to restore sensitivity and improve classification and survival prediction.
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HEXST: Hexagonal Shifted-Window Transformer for Spatial Transcriptomics Gene Expression Prediction
HEXST applies a hexagonal shifted-window Transformer with rotary positional encodings, contrast-sensitive training objectives, and single-cell priors to predict gene expression from histology slides, outperforming prior models on seven datasets while preserving spatial heterogeneity.
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Multi-Beholder: Biomarker Prediction for Low-Grade Glioma with Multiple Instance Learning and One-Class Classification
Multi-Beholder integrates one-class classification into multiple instance learning to predict LGG biomarker status from histopathology images, reporting AUCs of 0.973 on TCGA-LGG and 0.820 on an external Xiangya cohort.
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Federated Distillation for Whole Slide Image via Gaussian-Mixture Feature Alignment and Curriculum Integration
FedHD is a federated learning framework for whole slide images that distills one-to-one synthetic features aligned via Gaussian mixtures and progressively integrates cross-site features through curriculum learning to handle institutional heterogeneity.
- Thinking in Scales: Accelerating Gigapixel Pathology Image Analysis via Adaptive Continuous Reasoning