A zero-shot Llama-3.1-8B-Instruct, used as a mutation and crossover operator in directed evolution, outperforms a random-mutation evolutionary algorithm on four of five protein fitness benchmarks.
Deep diversification of an aav capsid protein by machine learning
1 Pith paper cite this work. Polarity classification is still indexing.
1
Pith paper citing it
fields
cs.LG 1years
2025 1verdicts
CONDITIONAL 1representative citing papers
citing papers explorer
-
Large Language Model is Secretly a Protein Sequence Optimizer
A zero-shot Llama-3.1-8B-Instruct, used as a mutation and crossover operator in directed evolution, outperforms a random-mutation evolutionary algorithm on four of five protein fitness benchmarks.