The paper introduces the EUII, derived from diagnostic likelihood ratios adjusted for sample size, to quantify evidentiary value per experimental unit and applies it to group-sequential adaptive designs for animal research.
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Balancing Evidentiary Value and Sample Size of Adaptive Designs with Application to Animal Experiments
The paper introduces the EUII, derived from diagnostic likelihood ratios adjusted for sample size, to quantify evidentiary value per experimental unit and applies it to group-sequential adaptive designs for animal research.