First-passage-time readout of kinetic proofreading yields exponential accuracy gains with more steps in noisy regimes, unlike product-concentration readout.
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Reliable ligand discrimination in stochastic multistep kinetic proofreading: First passage time vs. product counting strategies
First-passage-time readout of kinetic proofreading yields exponential accuracy gains with more steps in noisy regimes, unlike product-concentration readout.