In 2-period cluster randomized crossover trials with informative sizes, independence estimating equations always target the intended average treatment effect estimands, while nested exchangeable mixed model estimators do not.
Analysis of cluster randomized cross-over trial data: a comparison of methods.Statistics in Medicine.2007;26(2):274–289
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What is estimated in cluster randomized crossover trials with informative sizes? -- A survey of estimands and common estimators
In 2-period cluster randomized crossover trials with informative sizes, independence estimating equations always target the intended average treatment effect estimands, while nested exchangeable mixed model estimators do not.