HECLIP imputes spatial gene expression from H&E histology images using an image-centric contrastive loss and nearest-neighbor retrieval of reference profiles.
Spatial transcriptomics: Technologies, applications and experimental considerations
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HECLIP: Histology-Enhanced Contrastive Learning for Imputation of Transcriptomics Profiles
HECLIP imputes spatial gene expression from H&E histology images using an image-centric contrastive loss and nearest-neighbor retrieval of reference profiles.