The authors derive closed-form sample size formulas from Fisher's unit information matrix to target prediction confidence interval widths for linear regression models with continuous outcomes.
Uncertainty of risk estimates from clinical prediction models: rationale, challenges, and approaches
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A decomposition of Fisher's information to inform sample size for developing or updating fair and precise clinical prediction models -- Part 3: continuous outcomes
The authors derive closed-form sample size formulas from Fisher's unit information matrix to target prediction confidence interval widths for linear regression models with continuous outcomes.